A new prediction device can soon help identify patients with increased risk of mental damage associated with Alzheimer’s disease. Its operation is based on a few blood tests and simple medical standards.
Alzheimer’s disease is marked by the formation of protein deposits called amaloid peptides. SonSon. These reserves may be collected long before the visible memory issues appear. Some references exams, such as tomography. ExtractionExtraction That PosterronPosterron (PET-EMYLID) or analysis of FluidFluid SafeSafeThe spine (the brain around the brain and The spinal cordThe spinal cord, Through A PuncturePuncture lumbar (to collect this liquid in the bottom ThatThat), Detect these deposits.
However, these methods remain limited and expensive. The researchers then developed a more accessible mathematical model, based on social settlement standards (age, gender, education levels), academic tests and blood marks. The results were published. Alzheimer’s Research and Therapy.
Algorithm based on key bio -marker
Blood markers specifically target the amylide beta protein (AB42/40) and TAU protein (PTAU 181). Their change indicates the risk of neuronal deterioration. In addition, a special type of presence of EmbarrassmentEmbarrassment apolipoprotein e (it modules the gene transportation LipidsLipids In the body) increases the chances of developing the disease.
The algorithm relies on the analysis of these parameters to estimate whether an individual can offer excessive rates. amyloid platesamyloid plates In his mind. In practice, this device does not completely change the traditional exams, but it will refrain from invasive procedures for some patients.
Toward the first care of
The advantage of this strategy is based on the quick detection of Amyloid’s accumulation. Particularly rapidly identifying, thanks to new treatment Monoclonal AntibodiesMonoclonal Antibodies (MoleculesMolecules Those especially target to neutralize a particular protein), can be considered among those who have not yet proven dementia. Researchers are already planning to strengthen this model by combining PTAU217 proteins to improve the accuracy of the algorithm, such as PTAU217.
Summarized, it offers a new way for the point of view ScreeningScreeningThanks to a low -invading, fast and potentially more accessible diagnosis for a high number of patients. Such technological progress, ultimately, can make medical journey easier for people concerned about memory issues.
