Why is the risk of Parkinson’s disease growth in men like women double? A new American study shows that the immune system can play a key role in this difference.
While the World Parkinson’s Day will take place on April 11, a scientific discovery sheds new light on the neurodiganic disease that affects more than 10 million people worldwide. We know that men are twice as likely that women cause Parkinson’s disease, but the causes of this disparity are vague. Appeared in a recent study Journal of Clinical Investigation Partial Answers: According to the question, the male immune system that will react more aggressive reactions to Punk 1, an important protein of the brain.
Parkinson: What if our immune system played a key role?
Researchers at the Julla Immunology Institute in California have discovered that in men suffering from Parkinson’s disease, T lymphosis, immune cells, attack a major brain protein, called Pink 1. This protein, usually harmless, plays an integral role in the energy regulations of our brain cells. However, in some cases, the immune system confuses it with an agent PathogenicPathogenic And create a reaction that can lead to progressive destruction NeuronsNeurons.
The results of the study are clear: In men with Parkinson, the immune cells attacking Punk 1 are six times higher than in healthy subjects. In sick women, this multiplication is very low (0.7 times). If this immune difference is not enough to explain why men are more affected by the disease, it may prove to be an important factor among others in the development of Parkinson’s disease.
Towards modern screening and treatment?
This assumption opens the new approach. First, the possibility of developing a blood test that will indicate these specific immune cells already before SymptomSymptom. Currently, DiagnosticDiagnostic De Parkinson often interferes with late, when neurons are already widely destroyed. A ScreeningScreening Initially, it can be possible to slow the disease and slow the development of the disease.
This discovery can also pave the way for a new treatment to directly target the immune response. “” ” We can potentially develop ReignReign To prevent these cells ttNow we know why these cells target the brain “Immunologist explains Cecilia Landematum Aryniman. A approach that eventually can change the care of the disease by attacking one of its basic mechanisms, and no longer only happens to its symptoms.
